Resolution of Comorbidities
In Severe Obesity, the stored fat independently secretes a variety of hormones and other chemicals (called cytokines) which induce a chronic inflammatory disease state within the body. This metabolic abnormality is associated with the development of Pre-diabetes (also known as insulin resistance or glucose intolerance), Type 2 Diabetes, high blood pressure, dyslipidemia (high cholesterol, high triglycerides, low HDL), Metabolic Syndrome, atherosclerosis (hardening or narrowing of the arteries), heart disease, infertility, and other medical disorders.
Fortunately, these changes may not be permanent. Therefore, weight loss can result in a reduction or cessation in the secretion of these detrimental hormones and chemicals by the stored fat, resulting in improvement or complete resolution of the medical problems (comorbidities) associated with Severe Obesity.
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In addition to these chemical and hormonal effects, the weight of the stored fat has direct and indirect pressure effects that cause sleep apnea, back and weight-bearing joint pain, GERD, urinary incontinence, umbilical hernia, peripheral vein disease, ankle swelling, headaches, and dermatitis. These disorders are also reversible with weight loss.
Finally, the increased cancer risk and decreased average life expectancy associated with Severe Obesity are also abrogated with weight loss.
The following chart shows the resolution rates of these various comorbidities after bariatric surgery.
|Type 2 Diabetes||83% resolved|
|High Blood Pressure||52 - 92% resolved|
|High Cholesterol||63% resolved|
|Metabolic Syndrome||80% resolved|
|Heart Disease||82% risk reduction|
|Asthma||82% improved or resolved|
|Sleep Apnea||74 - 98% resolved|
|GERD||72 - 98% resolved|
|Bladder incontinence||44 - 88% resolved|
|Osteoartritis||41 - 76% resolved|
|Quality of Life||95% improved|
|Premature Death||89% reduction in 5 year death rate (related to obesity)|